Ryan Mathews and C.J. Spiller are the offensive rookie players who go into the season with the best chance for a big season. However, just because they will be given every chance from Day 1 to succeed, that doesn't mean that they will. Being a rookie in the NFL is never easy (especially for a rookie QB), that's why I would most definitely stay away from all rookie QBs. Here is a list of rookies that to varying degrees should be worthy of a fantasy pick. Remember if you decide to draft any rookies, be patient and don't give up on them so easily.